Neoderm®-ME/BE
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Composition

  • Epidermis
    • Human keratinocytes & melanocytes

Characteristics

  • Neoderm®-ME consists of all epidermal layers with added melanocytes in the basal layer (Figure 1~2).
  • A lighter and darker model can be chosen depending upon the level of melanin synthesis in melanocyte, Neoderm®-ME(Figure 3) and Neoderm®-BE (Figure 4).
  • It can be used to evaluate changes in melanin content in the skin following ultraviolet ray exposure or drug/cosmetics applications.
  • It can also be used to study the mechanism of melanogenesis by ultraviolet ray exposure or by hormones such as MSH (melanocyte-stimulating hormone) and ACTH (adrenocorticotropic hormone).

Applications

  • Lightening test
    • Fontana-Masson stain / DOPA stain
    • Melanin content assay
    • Tyrosinase activity
  • Melanogenesis Research
    • Measurement of changes in melenogenesis
      by hormones, cytokines or inhibitors

Well Type

6-well, 12-well

TEGO SCIENCE provides Contract Research Services using Neoderm®-ME and Neoderm®-BE